"My recent experience with the new HOMINGS methodology has been outstanding. We have been exploring oral microbial community structure as it relates to insulin resistance and impaired glucose tolerance using a cohort design. HOMINGS provides valid and reliable oral microbiome data in a quick and affordable fashion. As such, it has helped to dramatically expand the methodological capabilities and scope of molecular epidemiological studies. Collaborating with colleagues at Forsyth is a true pleasure."
Ryan Demmer, Ph.D.
Assistant Professor of Epidemiology
Co-Director, Epidemiology and Population Health Summer Institute at Columbia (EPIC)
Columbia University Medical Center
New York, NY
"I have had the pleasure of working very closely with Dr. Paster and his team for several years on studies of the oral microbiome in pediatric inflammatory bowel disease. We have found HOMIM to be an incredibly useful and easy tool to work with and have learned a tremendous amount about a topic previously unstudied. Their latest innovation, the HOMINGS platform, has provided us with species-level identification data that are more comprehensive than HOMIM, user-friendly and at a much lower cost. We look forward to a continued wonderful collaboration with Dr. Paster and his team."
Michael Docktor, M.D.
Gastroenterologist, Center for Inflammatory Bowel Disease
Clinical Director of Innovation
Director of Clinical Mobile Solutions
Boston Children's Hospital
Harvard Medical School
"My experiences with the new methodology and staff have been outstanding. I have been exploring microbial communities in various environments both in my own research as well as in undergraduate teaching laboratories. Students appreciate obtaining data reliably and quickly. Working and collaborating with Dr. Paster and his team has been an incredibly rewarding experience.”
Vanja Klepac-Ceraj, Ph.D.
“Our laboratory has been collaborating with Dr. Bruce Paster at the Forsyth Institute over the past 12 years on identification of oral microbial etiology of various human diseases. The recent development of HOMINGS has considerably advanced our ability to design experimental approaches to better understand bacterial interactions at the species level as well as interactions of bacteria with their human host. The most beneficial aspect of HOMINGS is the sheer number of species identified. HOMINGS identified approximately 600 species contained in our dental plaque samples, compared to approximately 300 species identified in the HOMIM data set of those same samples. By also reporting the number of hits identified to each species, with hit numbers ranging from 1 to just under 86,000, HOMINGS is more informative as to the magnitude of presence of each species compared to the HOMIM intensity scale system. Support from the members of the core lab for HOMINGS data analysis has been timely and informative with a great spirit of teamwork.”
Farah K. B. Mougeot, Ph.D.
Director, Oral Medicine Research Laboratory
Carolinas HealthCare System
"We have used HOMINGS to identify microbial compositions in human saliva samples from healthy and celiac disease patients. It has been an outstanding experience to work with Bruce and his team. The turnaround time for sample analysis was short, and bacterial identifications were provided in publishable Figure formats. The HOMINGS team is exceptionally well trained and knowledgeable on the topic."
Eva J. Helmerhorst, M.S., Ph.D.
Henry M. Goldman School of Dental Medicine
Dept. Periodontology and Oral Biology